Esomeprazole Magnesium is used to treat:
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Maxpro Mups 40mg Tablet contains Esomeprazole, which is classified as a Proton Pump Inhibitor (PPI). It is primarily used for the treatment of various conditions related to excessive stomach acid production.
Maxpro Mups 40mg Tablet is commonly prescribed for the following conditions:
Gastroesophageal reflux disease (GERD): It helps relieve symptoms such as heartburn, acid reflux, and inflammation of the esophagus caused by the backflow of stomach acid into the esophagus.
Stomach ulcers and Helicobacter pylori infection: It is used in combination with antibiotics to treat stomach ulcers or intestinal ulcers caused by Helicobacter pylori infection.
NSAID-induced ulcers: It is prescribed to prevent and treat ulcers in the upper part of the gut caused by the use of non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen or aspirin.
Zollinger-Ellison syndrome: It is used to manage the excessive production of stomach acid associated with a rare condition called Zollinger-Ellison syndrome, which involves the presence of a tumor in the pancreas.
Maxpro Mups 40mg Tablet should not be taken by individuals with severe kidney or liver failure. In pregnant women, it should only be used if considered necessary by a doctor, and it is not recommended for breastfeeding women. It is also not recommended for children and adolescents under 12 years of age.
The most common side effects of Maxpro Mups 40mg Tablet include headaches, diarrhea, stomach pain, constipation, flatulence, nausea, and vomiting. If any of these symptoms worsen over time, it is advisable to contact your physician for further guidance.
It's important to follow your doctor's instructions regarding the dosage and duration of treatment with Maxpro Mups 40mg Tablet. If you have any concerns or experience any unexpected side effects, consult your doctor for proper evaluation and advice.
Caution must be taken. Avoid consuming alcohol along with Maxpro Mups 40mg Tablet
Maxpro Mups 40mg Tablet should be avoided by pregnant women. However, one must consult a doctor to know the risks and benefits associated with it.
This medication should not be used by breastfeeding mothers. Doctor consultation is recommended.
Maxpro Mups 40mg Tablet shows side effects like dizziness and blurred vision which can affect driving ability. If you experience any such symptoms, do not drive.
Maxpro Mups 40mg Tablet should be used with caution in patients with severe kidney problems. Consult your doctor before taking Maxpro Mups 40mg Tablet.
Maxpro Mups 40mg Tablet should be used with caution in patients with severe liver problems. Consult your doctor before taking Maxpro Mups 40mg Tablet.
Esomeprazole
Maxpro Mups 40mg Tablet decreases the acid production in your stomach. It also fastens the healing process for ulcers.
Maxpro Mups 40 is a medication that lessens the quantity of acid your stomach produces. Heartburn, acid reflux, and issues with your food pipe are all treated with it. Stomach ulcers can also be prevented and treated with them. Maxpro Mups 40 should be taken as prescribed by your doctor.
Esomeprazole is a proton pump inhibitor (PPI) that works by inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells of the stomach. This inhibition reduces the production of gastric acid, thereby suppressing gastric acid output and acidity in the stomach.
Esomeprazole is the S-isomer of omeprazole, which means it is the single optical isomer of omeprazole. This single isomer form of the drug provides superior acid control compared to the racemic mixture of proton pump inhibitors, which contain both the S and R isomers. The S-isomer of esomeprazole is responsible for the majority of its acid-suppressing effects.
By specifically targeting the H+/K+ ATPase enzyme, esomeprazole effectively and selectively reduces the production of gastric acid, providing relief from conditions such as gastroesophageal reflux disease (GERD), stomach ulcers, and other acid-related disorders.
Here are the recommended doses for Maxpro Mups 40mg Tablet based on different age groups and conditions:
Adult Dose:
Elderly: No dosage adjustment is needed.
Hepatic Impairment:
Child Dose: The doses for children depend on the specific condition and age group. Here are some examples:
12 years: 20-40 mg orally once daily for up to 8 weeks.
12 years: 20-40 mg orally once daily for 4-8 weeks.
Renal Dose: No dosage adjustment is needed for patients with renal impairment.
It is important to follow your doctor's instructions regarding the dose and duration of Maxpro Mups 40mg Tablet. Take the medication as directed, with or without food, and swallow it with a glass of water. Do not crush or chew the tablets. The correct dose and duration of treatment will depend on your age, body weight, and the specific condition being treated.
It is important to be aware of potential drug interactions when taking Maxpro Mups 40mg Tablet. Here are some specific interactions to consider:
Interaction with Lab Test: Maxpro Mups 40mg Tablet may interfere with the neuroendocrine/carcinoid tumor test, potentially leading to a false-positive result. It is advisable to avoid using this medication while undergoing this specific diagnostic test.
Interaction with Medicines:
Clopidogrel: Maxpro Mups 40mg Tablet should not be used in combination with clopidogrel, a medication used to prevent blood clots. Concomitant use may reduce the effectiveness of clopidogrel.
Ketoconazole: Taking Maxpro Mups 40mg Tablet with ketoconazole, an antifungal medication, may increase the levels of esomeprazole (the active ingredient) in the blood. Close monitoring is recommended.
Methotrexate: Concurrent use of Maxpro Mups 40mg Tablet and methotrexate, a medication used to treat certain types of cancer and autoimmune diseases, may increase the risk of methotrexate toxicity. Caution is advised, and monitoring of methotrexate levels and potential side effects is necessary.
Warfarin: Maxpro Mups 40mg Tablet may interact with warfarin, an anticoagulant (blood thinner), and increase the risk of bleeding. Regular monitoring of blood clotting parameters is essential.
Nelfinavir: Nelfinavir, a medication used in the treatment of HIV infection, may decrease the effectiveness of Maxpro Mups 40mg Tablet. Consider alternative therapies or close monitoring if co-administration is necessary.
Digoxin: Concurrent use of Maxpro Mups 40mg Tablet and digoxin, a medication used for heart conditions, may increase the levels of digoxin in the blood. Regular monitoring of digoxin levels and potential side effects is recommended.
Interaction with Disease: Patients with liver disease, osteoporosis (a condition characterized by weakened bones), and hypomagnesemia (low levels of magnesium in the blood) should avoid taking Maxpro Mups 40mg Tablet or use it with caution. These conditions may increase the risk of adverse effects or require dosage adjustments.
It is essential to inform your healthcare provider about all medications, supplements, and medical conditions you have before starting Maxpro Mups 40mg Tablet to ensure safe and effective use. They can provide personalized advice and guidance based on your specific situation.
During pregnancy, there is limited data available on the use of esomeprazole (the active ingredient in Maxpro Mups 40mg Tablet). Esomeprazole is the S-isomer of omeprazole, and while available epidemiologic data on omeprazole use during the first trimester of pregnancy do not indicate an increased risk of major congenital malformations or adverse pregnancy outcomes, there are no well-controlled studies specifically conducted with esomeprazole.
Reproduction studies in animals (rats and rabbits) have shown dose-dependent embryo-lethality with omeprazole at doses that were approximately 3.4 to 34 times higher than the oral human dose of 40 mg, based on body surface area. However, animal studies may not always directly correlate with human response.
Regarding lactation, limited data suggest that omeprazole, the racemic mixture of which esomeprazole is an enantiomer, may be present in human milk. There are no clinical data available on the effects of esomeprazole on breastfed infants or milk production. When considering the use of esomeprazole in breastfeeding women, it is important to weigh the developmental and health benefits of breastfeeding against the mother's clinical need for therapy and the potential adverse effects on the breastfed infant from treatment or the underlying maternal condition.
It is crucial to consult with a healthcare professional or your doctor regarding the use of Maxpro Mups 40mg Tablet during pregnancy or while breastfeeding. They can provide personalized advice based on your specific situation and help determine the best course of action.
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Store in a cool & dry place below 25ºC, and protect from light. Keep out of reach of children.
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